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CASM PI

 
Dongcai Liang, Ph.D, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
Structural biology
Liang’s group is mainly engaged in structural biology study which is focused on determining the structure of biomacromolecules and the macromolecular complexes through the X-ray protein crystallography, and understanding the relationship between the structure and the function of biomacromolecules. More ...  
   
   
 
Fuyu Yang, Ph.D, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
Modulation of cell fate by lipid-protein interactions within intracellular membrane structures
The main research focus of our group is on the modulation of cell fate by lipid-protein interactions within intracellular membrane structures (especially mitochondria and lysosomes). 1. The modulation and effects of lipid-protein interactions within mitochondria and lysosomes on the induction of apoptosis and autophagy of cells. More ... 
   
   
 
Zhixin Wang, Ph.D, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
Biochemistry and structural biology
I have published more than 70 papers in biochemistry and structural biology, and my present research interests center on the physical chemistry of protein, kinetics of enzyme catalysis and regulation, protein-ligand interaction and prediction of protein three-dimensional structure. More ... 
   
   
 
Zhizhen(Chih-chen)  Wang, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
Protein folding, molecular chaperones and foldases
Our group has been studying protein folding during past decades, particularly focusing on molecular chaperones and foldases. We proposed the hypothesis that “protein disulfide isomerase (PDI) is both an enzyme and a chaperone”. Then we systematically characterized the novel chaperone activity of protein disulfide isomerase, More ...
   
   
 
Zihe Rao, Ph.D, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
Study of the three-dimensional structures of significant proteins and viruses related to human infection disease or with important physiological functions, as well as in innovative drug discovery
Zihe Rao is a structural virologist, mainly engaged in the study of the three-dimensional structures of significant proteins and viruses related to human infection disease,  More ... 
   
   
 
Aike Guo, Ph.D, Prof., CASM
Principal Investigator
IBP Division - State Key Laboratory of Brain & Cognitive Sciences
Learning /Memory of Drosophila
He has established the first Laboratory of Learning /Memory of Drosophila in China at IBP in 1993. He has been engaged in the study about the learning, memory, selective attention, decision making, circadian clock, sleep and memory relationship ,male-male courtship, as well as the neurodegenerations in flies. More ...
   
   
 
Lin Chen, Ph.D, Prof., CASM
Principal Investigator
IBP Division - State Key Laboratory of Brain & Cognitive Sciences
Experimental psychology, cognitive science, and human brain mapping
Experimental psychology, cognitive science, and human brain mapping, particularly visual cognition. More ... 
 
   
   
 
Dacheng Wang, Ph.D, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
The three dimensional structures of proteins and their structure-function relationships and the protein engineering
The research of our group has focused on the three dimensional structures of proteins and their structure-function relationships and the protein engineering of for a rather long time. Previous research subjects included protein hormones, polypeptide neuron toxins,  More ...
   
   
 
Wenrui Chang, Ph.D, Prof., CASM
Principal Investigator
IBP Division - National Laboratory of Biomacromolecules
Structural and functional analysis of biomacromolecules
Prof. Chang is working on the structural and functional analysis of biomacromolecules (including Insulin, Earthworm Fibrinolytic Enzymes, Metalloproteins, Phycobiliproteins and etc.) for many years. For the past decade, the main research focus of our group is on structural studies of photosynthesis related proteins. Photosynthesis, More ... 
   
   
 
Runsheng Chen, Prof., CASM
Principal Investigator
IBP Division - Beijing Key Laboratory of Noncoding RNA
Theoretical biology and bioinformatics
Professor Runsheng Chen is one of the pioneer scholars developing the researches on theoretical biology and bioinformatics in China. For more than twenty years, Prof. Chen has led his group to perform a series of systemic researches in the field of bioinformatics, including the whole genome assembly and annotation for T. tengcongensis B4 (the first bacterium genome completely sequenced in China), More ...
   
   
Xiyun Yan, Ph.D, Prof., CASM 
Principal Investigator
IBP Division -Chinese Academy of Sciences Key Laboratory of Infection and Immunity
Humanized antibody for tumor therapy,development of nanozyme mimetics
1. Discovery of the critical role of a cell membrane molecule, CD146, in angiogenesis and development of a humanized antibody for tumor therapy. 2. Discovery of the enzyme-mimetic activity of magnetite nanomaterials and development of novel technology for tumor diagnosis, More...  
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