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Li Liu, Ph.D, Prof.

Principal Investigator, IBP Deputy Director

State Key Laboratory of Brain & Cognitive Sciences, IBP

How the central nervous system translates environmental stimuli to behavior

E-mail:liuli@ibp.ac.cn,Tel:010-64888550

Fax:010-64871293,Zip code:100101

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Biography & Introduction

Education and Professional Experience

1985 -1989: B. Sc. in Biophysics, Nankai University, Tianjin

1991 -1996: Ph. D. in Biophysics, Institute of Biophysics of CAS, Beijing

1996 -1997: Assistant Professor, Institute of Biophysics of CAS, Beijing

1997 -1999: Postdoctoral Research in Wuerzburg University, Germany

1999 - Present: Professor of Institute of Biophysics of CAS, Beijing

Research Interests

In response to the environmental stimuli, fruit fly-Drosophila melanogaster exhibits a diversity of behavioral activities from feeding and locomotion to cognitive processes. Using a variety of experimental approaches, ranging from behavioral to molecular, our lab seeks to study how the central nervous system translates environmental stimuli to behavior. We attempt to elucidate the structure and function of the brain in relation to the production of specific behavior in Drosophila.

Selected Publications

1. Qionglin Peng, Yijin Wang, Meixia Li, DeliangYuan, Mengbo Xu, Changqing Li, Zhefeng Gong, Renjie Jiao, Li Liu (2016) cGMP-dependent protein kinase encoded by foragingregulates motor axon guidance in Drosophila by suppressing Lola function. The Journal of Neuroscience, 36(16):4635-4646.

2. Chao Guo, Yifei Du, Deliang Yuan, Meixia Li, Haiyun Gong, Zhefeng Gong, Li Liu (2014) A conditioned visual orientation requires the ellipsoid body in Drosophila. Learning & Memory, 22:56-63.

3. Jiangqu Liu, Zhefeng Gong, Li Liu (2014) γ-glutamyl transpeptidase 1 specifically suppresses green-light avoidance via GABAA receptors in Drosophila. J Neurochemestry, 130:408-418.

4. Xuebo Cheng, Huoqing Jiang, Weizhe Li, Hailong Lv, Zhefeng Gong, Li Liu (2013)ten-aaffects the fusion of central complex primordia in Drosophila. PLOS One, 8(2): e57129.

5. Meixia Li, Shengyun Wen, Xiangqian Guo, Baoyan Bai, Zhefeng Gong, Xiaojun Liu, Yijin Wang, Yanqiong Zhou, Xiaowei Chen, Li Liu, Runsheng Chen (2012) The novel long non-coding RNA CRG regulatesDrosophila locomotor behaviour. Nucleic Acids Research, 40(22):11714-11727.

6. Yanqiong Zhou, Xiaoxiao Ji, Haiyun Gong, Zhefeng Gong, Li Liu (2012) Edge detection depends on achromatic channel in Drosophila melanogaster. Journal of Experimental Biology, 215:3478-3487.

7. Huoqing Jiang, Qinlong Hou, Zhefeng Gong, Li Liu (2011) Proteomic and transcriptomic analysis of visuallong-term memory in Drosophila melanogaster. Protein & Cell, 2(3):215-222.

8. Zhefeng Gong, Jianqu Liu, Chao Guo, Yanqiong Zhou, Yan Teng, Li Liu (2010) Two pairs of neuronsin central brain control Drosophila innate light preference. Science, 330:499-502.

9. Yan Xiong, Hailong Lv, Zhefeng Gong, Li Liu (2010) Fixation and locomotor activity are impairedby inducing tetanus toxin expressionin adult Drosophila brain. Fly,3 (4):194-203.

10. Weizhe Li, Yufeng Pan, Zhipeng Wang, Haiyun Gong, Zhefeng Gong, Li Liu (2009) Morphological characterization ofsingle fan-shaped body neurons in Drosophila melanogaster. Cell Tissue Research, 336:509-519.

11. Yufeng Pan, Yanqiong Zhou, Chao Guo, Haiyun Gong, Zhefeng Gong, Li Liu (2009) Differential roles of the fan-shaped body and the ellipsoid body in Drosophila visual pattern memory. Learning & Memory,16:289-295.

12. Zhipeng Wang, Yufeng Pan, Weizhe Li, Huoqing Jiang, Lazaros Chatzimanolis, Jianhong Chang, Zhefeng Gong, Li Liu (2008) Visual pattern memory requires foraging function in the central complex of Drosophila. Learning & Memory, 15:133-142.

13. Gang Liu, Holger Seiler, Ai Wen, Troy Zars, Kei Ito, Reinhard Wolf, Martin Heisenberg, Li Liu (2006) Distinct memory traces for two visualfeatures in the Drosophila brain. Nature, 439:551-556.

14. Li Liu, Reinhard Wolf, Roman Ernst, Martin Heisenberg (1999) Context generalization in Drosophila visual learning requires the mushroom bodies. Nature, 400:753-756.

  

 

From Li Liu,  2017-10-30 update

 

 

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Institute of Biophysics, CAS    Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Tel:8610-64889872    Fax: 8610-64871293    E-mail: office@ibp.ac.cn