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Wei Ji, Ph.D

Members of the Youth Innovation Promotion Association,CAS
Single molecule detection and superresolution correlative light and electron microscopy
Tel:  010-64888846
Fax: 010-64888524
Zip code: 100101 

Biography & Introductions

2001.09-2005.06 B.Sc. in Biomedical engineering, Huazhong University of Science and Technology, China  

2005.09-2010.07 Ph.D. in Biophsics, Institute of Biophysics, CAS

2010.08-2011.12 Assistant professor, Institute of Biophysics, CAS

2012.01-2016.12 Associate professor, Institute of Biophysics, CAS

2017.01-Present  Professor, Institute of Biophysics, CAS

Research Interest  

Try to use single molecule detection (SMD) and superresolution correlative light and electron microscopy (sCLEM) methods to solve problems that now faced by biological researchers.

Selected publications

1. Lusheng Gu, Yuanyuan Li, Shuwen Zhang, Yanhong Xue, Weixing, DongLi, Tao Xu*, Wei Ji*. (2019) Molecular resolution imaging by repetitive optical selective exposure, Nature Methods, DOI:10.1038/s41592-019-0544-2.
2. Li Y, Xue Y, Xu X, Wang G, Liu Y, Wu H, Li W, Wang Y, Chen Z, Zhang W, Zhu Y, Ji W, Xu T, Liu L, Chen Q. (2018) A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. EMBO J. doi: 10.15252/embj.201798786. [Epub ahead of print] 
3. Xu X, Xue Y, Tian B, Feng F, Gu L, Li W, Ji W*, Xu T*.(2018) Ultra-stable super-resolution fluorescence cryo-microscopy for correlative light and electron cryo-microscopy. Sci China Life Sci. 61(11):1312-1319. doi: 10.1007/s11427-018-9380-3. Epub 2018 Nov 2.
4. Zou W, Fu J, Zhang H, Du K, Huang W, Yu J, Li S, Fan Y, Baylis HA, Gao S, Xiao R, Ji W*, Kang L*, Xu T*.(2018) Decoding the intensity of sensory input by two glutamate receptors in one C. elegans interneuron. Nat Commun. 9(1):4311. doi: 10.1038/s41467-018-06819-5.         
5. Xi Lan#,Chunyan Fan#,Wei Ji,Fuyun Tian,Tao Xu*,Zhaobing Gao*. (2016) Grafting voltage and pharmacological sensitivity in potassium channels. Cell Research  (2016) :1-11.
6. Liu B#, Xue Y#, Zhao W#, Chen Y, Fan C, Gu L, Zhang Y, Zhang X, Sun L, Huang X, Ding W, Sun F, Ji W*, Xu T*. (2015) Three-dimensional super-resolution protein localization correlated with vitrified cellular context. Sci Rep. (2015)5:13017.
7. Gu L#, Sheng Y#, Chen Y#, Chang H, Zhang Y, Lv P, Ji W*, Xu T*. (2014)High-density 3D single molecular analysis based on compressed sensing. Biophys J. 106(11):2443-9.
8.  Zhang Y#, Gu L#, Chang H#, Ji W#, Chen Y, Zhang M, Yang L, Liu B, Chen L*, Xu T*. (2013) Ultrafast, accurate, and robust localization of anisotropic dipoles. Protein & Cell. 4(8): 598–606
9. Mingshu Zhang#, Hao Chang#, Yongdeng Zhang#, Junwei Yu, Lijie Wu, Wei Ji, Juanjuan Chen, Bei Liu, Jingze Lu, Yingfang Liu, Junlong Zhang, Pingyong Xu*, and Tao Xu*. (2012) Rational design of true monomeric and bright photoactivatable fluorescent proteins. Nature methods. doi:10.1038/nMeth.2021
10. Hao Chang#, Mingshu Zhang#, Wei Ji#, Juanjuan Chen, Yongdeng Zhang, Bei Liu, Jingze Lu, Junlong Zhang, Pingyong Xu*, and Tao Xu*. (2012) A unique series of reversibly switchable fluorescent proteins with beneficial properties for various applications. Proc Natl Acad Sci U S A. 109(12):4455-60.
11. Yu Chen#, Yan Wang#, Wei Ji#, Pingyong Xu* and Tao Xu*. (2008)A pre-docking role for microtubules in insulin-stimulated glucose transporter 4 translocation. FEBS J. 275(4):705-12
12. Wei Ji#, Pingyong Xu#, Zhengzheng Li#, Jingze Lu, Lin Liu, Yi Zhan, Yu Chen, BertilHille, Tao Xu*, and Liangyi Chen*. (2008) Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci USA. 105(36):13668-73.



From Weir Ji, 2019-10-22 update


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Institute of Biophysics, CAS    Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Tel:8610-64889872    Fax: 8610-64871293    E-mail: office@ibp.ac.cn