 | Na Yang, Ph.D, Prof. Winner of the Excellent Young Scientists Excellent Member of the Youth Innovation Promotion Association of CAS Structural mechanisms of epigenetics Fax: 010-64888023, Zip code: 100101 |
Biography & Introduction
1996.09-2000.07 B.Sc., Biophysics, Peking University, Beijing, China
2000.09-2005.07 Ph.D., Structural biology, Institute of Biophysics, CAS
2005.07-2006.03 Research assistant, Institute of Biophysics, CAS
2006.04-2008.10 Postdoctoral associate, Peking University
2008.10-2013.12 Associate professor, Institute of Biophysics, CAS
2013.12-2019 Professor, Institute of Biophysics, CAS
2015.10-2019 Professor, University of the Chinese Academy of Sciences (UCAS)
Awards and Honors
2016 Excellent Young Scientists Fund
2015 Excellent Member of the Youth Innovation Promotion Association of CAS
2012 Second prize of Young Scientist Forum, the Chinese Society of Biochemistry and Molecular Biology
2011 Lu Jiaxi Young Talent Award of Chinese Academy of Sciences
2006 First prize of Chinese Postdoctor Award
2005 President prize of Chinese Academy of Sciences
2004 First prize of Director Scholarship of Institute of Biophysics
2001 Excellent Graduate Student in the graduate school of CAS
Professional Services
2008-2009 Secretary, Chinese Crystallographic Society
2009- Secretary General, Molecular Biophysics Section of the Chinese Biophysical Society
2014- Consultant, Commission on Biological Macromolecules, IUCr
2015- Member, Youth Federation of the Chinese Academy of Sciences
Dr. Na Yang has been carrying out structural mechanism studies of epigenetics, including histone modifications and nucleosome assembly, as well as RNA-protein interactionsduring the mRNA localization procedure. During her 16-year research in structural biology, has published 31 SCI research articles in prestigious journals such as Science,NSMB, PNAS, Genes & Dev., JBC, and written 1 book chapterof Handbook of Proteolytic Enzymes (ISBN 9780123822192, Chapter 681).
Selected Publications
1. Fu, W. Q., Liu, N., Qiao, Q., Wang, M., Min, J. R., Zhu, B.*, Xu, R. M.* and Yang, N.* (2016) Structural Basis for Substrate Preference of SMYD3, A SET Domain-containing Protein Lysine Methyltransferase. J. Biol. Chem., Vol. 291, 9173-9180.
2. Yang, N.*, Yu, Z. Y., Hu, M. L.,Wang, M., Lehmann, R.* and Xu, R. M.* (2015) Structure of Drosophila Oskar reveals a novel RNA binding protein. Proc. Natl. Acad. Sci .USA, Vol. 112, 11541-11546.
3. Cao, D.F., Wang, M., Qiu X.Y., Liu D.X., Jiang H.L., Yang N.* and Xu R.M*. (2015) Structural basis for allosteric, substratedependentstimulation of SIRT1 activityby resveratrol. Genes & Dev. Vol. 29, 1316-1325.
4. Wang, H., Wang, M., Yang, N.* and Xu, R. M.*(2015) Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2. Protein & Cell, Vol. 6, 693-697.
5. Yang, D. X., Fang, Q. L., Wang, M., Ren, R., Wang, H., He, M., Sun, Y. W., Yang, N.* and Xu, R. M.* (2013) Nα-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain. Nat. Struct. Mol. Biol., Vol. 20, 1116-1118.
6. Yang, N.* and Xu, R. M.* (2013) Structure and function of the BAH domain in chromatin biology. Crit. Rev. Biochem. Mol. Biol., Vol. 48, 211-221.
7. Yang, N.*, Wang, W., Wang, Y., Wang, M., Zhao, Q., Rao, Z., Zhu, B.* and Xu, R. M.* (2012) Distinct mode of methyl-H3K4 recognition by tandem tudor-like domains of Spindlin1. Proc. Natl. Acad. Sci .USA, Vol. 109, 17954-17959.
8. Yang, N., Li, D. F., Feng, L., Xiang, Y., Liu, W., Sun, H. and Wang, D. C.* (2009) Structural Basis for the Tumor Cell Apoptosis-Inducing Activity of an Antitumor Lectin from the Edible Mushroom Agrocybe aegerita. J. Mol. Biol., Vol. 387(3), 694-705.
9. Yang, N., Nan, J., N., Brostromer, E., Hatti-Kaul, R., and Su, X. D.* (2008) Crystal structure of an alkaline serine protease from Nesterenkonia sp. defines a novel family of secreted bacterial proteases. Proteins: Structure, Function and Bioinformatics, Vol. 73(4), 1072-1075.
10. Liu, W.#, Yang, N.#, Ding, J. J., Huang R. H., Hu, Z. and Wang, D. C.* (2005) Structural mechanism governing the quaternary organization of monocot mannose-binding lectin revealed by a novel monomeric structure. J. Biol. Chem., Vol. 280, 14865-14876. (#Co-first authors)
11. Yang, N., Tong X., Xiang, Y., Sun, H. and Wang, D. C.* (2005) Molecular character of an antitumour lectin from the edible mushroom Agrocybe aegerita. The Journal of Biochemistry, Vol. 138, 145-150.
12. Yang, N., Xiang, Y., Zhang, Y. and Wang, D. C.* (2005) Crystallization and preliminary crystallographic studies of the recombinant antitumour lectin from the edible mushroom Agrocybe aegerita. BBA: Proteins and Proteomics, Vol. 1751, 209-212.
13. Yang, N., Liang, Y., Xiang, Y., Sun, H. and Wang, D. C.* (2005) Crystallization and preliminary crystallographic studies of an antitumour lectin from the edible mushroom Agrocybe aegerita. Protein and Peptide Letters, Vol. 12, 705-707.
From Na Yang, 2017-01-10 update
