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Zhenyu Yu, Ph.D., Associate Prof.

Members of the Youth Innovation Promotion Association, CAS

National Laboratory of Biomacromolecules, IBP     

Structural and functional studies of mRNA post-transcription regulation

E-mail: yuzhenyu@moon.ibp.ac.cn,

Tel: 010-6488390    

Zip code: 100101

Chinese personal homepage  

Biography & Introduction

2003.09-2007.06 B.M., Nanjing Agricultural University, Nanjing, China

2007.09-2012.09 Ph.D. in Microbiology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China

2012.09-2015.12 Assistant Professor, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

2016.01-present Associate Professor, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences


NSFC Young Scientists Program - “Structure mechanism studies of oskar mRNA recognition by RNA-binding protein Smaug in Drosophila germ cell development”, 2015-2017, 250,000 RMB

Research interests

My research interests focus on structural and functional studies of protein-protein and protein-RNA complex that involved in mRNA splicing, processing and localization during the precedure of mRNA post-transcription regulation.

Selected publications(Co-first authors#,Co-corresponding authors*)

1. Na Yang#*, Zhenyu Yu#, Meng long Hu#, Mingzhu Wang, Ruth Lehmann*, Ruiming Xu*. Structure of Drosophila Oskar reveals a novel RNA binding protein. Proc Natl Acad Sci. 2015; 112(37):11541-6.

2. Zhenyu Yu, Hong Zhu, Guosong Zheng, Weihong Jiang*, Yinhua Lu*. A genome-wide transcriptomic analysis reveals diverse roles of the two-component system DraR-K in the physiological and morphological differentiation of Streptomyces coelicolor. Applied Microbiology and Biotechnology. 2014; 98(22):9351-63.

3. Zhenyu Yu, Hong Zhu, Fujun Dang, Weiwen Zhang, Zhongjun Qin, Sheng Yang, Huarong Tan, Yinhua Lu*, Weihong Jiang*. Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor. Molecular Microbiology. 2012; 85(3):535-556.

4. Yinhua Lu, Juanmei He, Hong Zhu, Zhenyu Yu, Rui Wang, Fujun Dang, Sheng Yang, Weihong Jiang. An orphan histidine kinase, OhkA, regulates both secondary metabolism and morphological differentiation in Streptomyces coelicolor. Journal of Bacteriology. 2011; 193: 3020-3032.

5. Dan Shu, Lei Chen, Weihua Wang, Zhenyu Yu, Cong Ren, Sheng Yang, Yinhua Lu*, Weihong Jiang*. afsQ1-Q2-sigQ is a pleiotropic but conditionally required signal transduction system for both secondary metabolism and morphological development in Streptomyces coelicolor. Applied Microbiology and Biotechnology. 2009; 81: 1149-1160.


From Zhenyu Yu, 2019-11-22

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Institute of Biophysics, CAS    Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Tel:8610-64889872    Fax: 8610-64871293    E-mail: office@ibp.ac.cn