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Peihua Chen, Ph.D, Associate Professor

Members of the Youth Innovation Promotion Association, CAS

State Key Laboratory of Brain & Cognitive Sciences, IBP


E-mail: chenpeihua@ibp.ac.cn

Tel: 010-64880905

Zip code: 100101

Chinese personal homepage 

Biography & Introduction 

2001—2005 B.S. in Biomedical Engineering, University of Electronic Science and Technology of China

2005—2010 Ph. D in Biomedical Engineering, Zhejiang University

2010—2014 Postdoctoral associate, Institute of Biophysics, CAS

2014—2019 Associate professor, Institute of Biophysics, CAS

Research interest 

1. Molecular and cellular mechanism of synaptic vesicle release

2. High accuracy detection techniques and methods for synaptic vesicles signals in CNS in vivo


2005 Outstanding Graduate Award, Sichuan Province

2009 Chu Kochen Award, Zhejiang University

2010 Outstanding Graduate Award, Zhejiang Province


1. National Natural Science Foundation (General Program), Synaptic vesicle fusion and quantal neurotransmitter release, 2016/01—2019/12 

2. National Natural Science Foundation Youth Fund, Mechanism of Ca2+ influx driven single synaptic vesicle exocytosis and endocytosis, 2013/01—2015/12

Selected publications

1. Zhang W, Chen P*#, Zhou L, et al. A biomimetic bioelectronic tongue: A switch for On- and Off- response of acid sensations. Biosens and Bioelectron. 2016, in press.  

(* co-first author and # co-corresponding author)

2.Chen P, Wu J, Zhao J, et al. PKD2L1/PKD1L3 channel complex with an alkali-activated mechanism and calcium- dependent inactivation. Eur Biophys J. 2015, 44, 483-492

3. Dai J, Chen P, Tian H, Sun J. Spontaneous Vesicle Release Is Not Tightly Coupled to Voltage-Gated Calcium Channel- Mediated Ca2+ Influx and Is Triggered by a Ca2+ Sensor Other Than Synaptotagmin-2 at the Juvenile Mice Calyx of Held Synapses. J. Neurosci. 2015, 35(26), 9632-9637.

4.Chen P, Zhang W, Chen Pg, et al. A serotonin-sensitive sensor for investigation of taste cell-to-cell communication. Biosens and Bioelectron. 2011, 26, 3054-3058.

5.Chen P, Wang B, Cheng G, Wang P. Taste receptor cell-based biosensor for taste specific recognition based on temporal firing. Biosens and Bioelectron. 2009, 2515, 228-233.

6.Chen P, Liu X, Wang B, et al. A biomimetic taste receptor cell-based biosensor for electrophysiology recording and acidic sensation. Sensor Actuat B-Chem. 2009, 139 (2), 576-583.

7.Chen P, Zhang W, Zhou J, et al. Development of planar patch clamp technology and its application in the analysis of cellular electrophysiology. Prog Nat Sci. 2009, 19 (2), 153-160.

8.Chen P, Liu X, Zhang W, et al. Modeling and simulation of ion channels and action potentials in taste receptor cells. Sci. China Ser. C, 2009, 52(11):1036-1047.

9.Chen P, Cheng G, Wang B, et al. Design of a novel acid-sensing biosensor based on taste neurons and LAPS, The 2nd Bioinformatics and Biomedical Engineering, 2008.

10.Wu C, Chen P, Yu H, et al. A novel biomimetic olfactory-based biosensor for single olfactory sensory neuron monitoring. Biosens and Bioelectron. 2009, 24(15), 1498-1502.

11.Wu C, Chen P, Yuan Q, Wang P. Response enhancement of olfactory sensory neurons -based biosensors for odorant detection. J. Zhejiang Univ Sci B, 2009, 10 (4), 285-290.


1. Chen Peihua,Sun Jianyuan,Shen Xuefeng,Dai Jinye,Zhang Shuli. “A patch clamp system for single vesicle exocytosis-endocytosis and the coupling between a single vesicle and calcium channels”(No. 201510104564.4)

2. Chen Peihua,Sun Jianyuan,Shen Xuefeng. “A low-noise temperature control system for patch clamp” (No. 201610676947.3)

3. Shen Xuefeng,Sun Jianyuan,Chen Peihua. “Submico/nanomicro carbon fiber electrode with high spatial resolution.”(No. 201610680442.4)

4. Shen Xuefeng,Sun Jianyuan,Chen Peihua, Zhang Shuli. “A novel carbon fiber electrode for patch amperometry syetem”(No. 201510104447.8)

5. Dai Jinye, Sun Jianyuan,Chen Peihua, Zhang Shuli. “A detection method for a single micro synaptic neuron electrical activities” (No. 201510657463.X)


From Peihua Chen, 2019-11-22

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Institute of Biophysics, CAS    Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Tel:8610-64889872    Fax: 8610-64871293    E-mail: office@ibp.ac.cn