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Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression

Author: Update time: 2009-09-02

By performing a systematic analysis on a mass of non-protein coding transcripts extracted from C. elegans, Prof. Runsheng Chen's group has found 100 novel ncRNA genes in the C. elegans genome, and identified two novel ncRNA classes (stem-bulge RNA and small nuclear-like RNA) and three ncRNA upstream motifs. Their analysis indicated that ncRNA has an independent transcriptional regulation system which is different from that of protein coding genes.

This work was published on GENOME RES (2006,16(1):20-29).

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