Towards developing a variant-proof SARS-CoV-2 vaccine, Cell Res, 2 Jan 2023
Cell Research, 2 January, 2023, DOI：https://doi.org/10.1038/s41422-022-00753-4
Towards developing a variant-proof SARS-CoV-2 vaccine
Hua Peng & Yang-Xin Fu
New targets for broad-spectrum vaccines are urgently needed to defend the variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In a recent study in Cell Research, Pang et al. reported a novel variant-proof SARS-CoV-2 vaccine targeting a transient intermediate conformational status of the HR domains in the S2 subunit.