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Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression. |
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2009-11-30 |
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Important achievements
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Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression
GENOME RES 2006,16(1):20-29 |
By performing a systematic analysis on a mass of non-protein coding transcripts extracted from C. elegans, Prof. Runsheng Chen's group has found 100 novel ncRNA genes in the C. elegans genome, and identified two novel ncRNA classes (stem-bulge RNA and small nuclear-like RNA) and three ncRNA upstream motifs. Their analysis indicated that ncRNA has an independent transcriptional regulation system which is different from that of protein coding genes.
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