Institute of Biophysics of Chinese Academy of Sciences

Nanozyme-activated prodrug strategy for targeted tumor catalytic therapy

Enzyme prodrug therapy which was introducedin 1985 is an attractive strategy for targeted cancer therapy with low systemic toxicity .HRP can catalyze the prodrug IAA to produce highly toxic free radical products and kill tumors effectively , so it has a broad application prospect in tumor treatment .However , conjugated antibody targeting is limited by missed target in vivo and acting outside tumor cells so as to limit its tumor killing effect .

Visual sensitivity adaptation depends on feedback signals from the representation of visual perception

The journal of Nature Communications on August 6 published latest findings by the team of Prof. HE Sheng with the State Key Laboratory of Brain and Cognitive Science at the Institute of Biophysics (IBP), the Chinese Academy of Sciences. The article, titled "Adaptation to feedback representation of illusory orientation produced from flash grab effect", explains that feedback signals in visual cortex play an important role in the orientation-selective adaptation of visual perception.

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2020-08-06

IBP organizes study on clean governance

Nanozyme-activated prodrug strategy for targeted tumor catalytic therapy

Visual sensitivity adaptation depends on feedback signals from the representation of visual perception

Scientific explanation of Lycium barbarum's traditional effects on strengthening muscles — modulating muscle fiber types to enhance muscle function in a manner similar to exercise

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IBP organizes study on clean governance

Research Progress

A novel electron-transport and proton-translocation coupling model revealed by the cryo-EM structure of the photosynthetic alternative complex III

Analyzing chromatin status of poised genes may provide a powerful tool to predict the transcription potential

S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid

Structural analysis for the post-fusion SARS-CoV spike glycoprotein

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