Enzyme prodrug therapy which was introducedin 1985 is an attractive strategy for targeted cancer therapy with low systemic toxicity .HRP can catalyze the prodrug IAA to produce highly toxic free radical products and kill tumors effectively , so it has a broad application prospect in tumor treatment .However , conjugated antibody targeting is limited by missed target in vivo and acting outside tumor cells so as to limit its tumor killing effect .
The journal of Nature Communications on August 6 published latest findings by the team of Prof. HE Sheng with the State Key Laboratory of Brain and Cognitive Science at the Institute of Biophysics (IBP), the Chinese Academy of Sciences. The article, titled "Adaptation to feedback representation of illusory orientation produced from flash grab effect", explains that feedback signals in visual cortex play an important role in the orientation-selective adaptation of visual perception.
The research article of Dr. CHEN Chang’s group titled "An extract of Lycium barbarum mimics exercise to improve muscle endurance through increasing type IIa oxidative muscle fibers by activating ERRγ" was published online in FASEB Journal on July 30, 2020.