Institute of Biophysics of Chinese Academy of Sciences

A novel electron-transport and proton-translocation coupling model revealed by the cryo-EM structure of the photosynthetic alternative complex III

A new research from the group of SUN Fei at Institute of Biophysics and the groups of XU Xiaoling and XIN Yueyong at Hangzhou Normal university was published on Science Advances .Entitled " Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii " .The researchers revealed the first high-resolution structures of alternative complex III ( ACIII ) from Roseiflexus castenholzii at both oxidized and reduced states .

Analyzing chromatin status of poised genes may provide a powerful tool to predict the transcription potential

In eukaryotic cells , the genomic DNA is hierarchically packaged by histones into chromatin .Chromatin structure and its plasticity play an important role in the activation and silencing of gene transcription , and determine the cell fate during differentiation and development .A study published online in Cell Reports with the title of " Analysis of Local Chromatin States Reveals Gene Transcription Potential during Mouse Neural Progenitor Cell Differentiation " , revealed the structural characteristics of poised genes .

S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid

Hsp70 proteins are a family of ancient and conserved molecular chaperones which are essential for life , and they often buffer the effects of internal and external stressors on cellular activity .Aging and cancer are often associated with long-term changes to Hsp70 expression levels and activity , while under the normal fluctuations of the cellular environment , Hsp70 undergoes more subtle and reversible changes to its abundance and activity .

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2020-08-06

IBP organizes study on clean governance

A novel electron-transport and proton-translocation coupling model revealed by the cryo-EM structure of the photosynthetic alternative complex III

Analyzing chromatin status of poised genes may provide a powerful tool to predict the transcription potential

S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid

News Center

IBP organizes study on clean governance

Research Progress

Structural analysis for the post-fusion SARS-CoV spike glycoprotein

Dr. ZHU Bing's group dissected the kinetics and mechanisms of mitotic DNA methylation maintenance and their contributionsin aging-associated methylome deterioration

Research team reveals the novel catalytic regulatory mechanism of ubiquitination and deubiquitination mediated by pathogens

Chinese scientists achieve breakthrough in protein synthesis

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