
Ning Liu, Ph.D, Prof.
-
Principal Investigator
State Key Laboratory of Cognitive Science and Mental Health, IBP
Research Interests: Neural mechanisms underlying social cognition and its related brain disorders
Email: liuning@ibp.ac.cn
Tel: 010-64888550
Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Chinese personal homepage
- Biography
1997 - 2002 University of Science and Technology of China, B.S. in Biological Sciences, B.E. in Computer Science and Technology
2004 - 2007 Kunming Institute of Zoology, Chinese Academy of Sciences, Ph.D. in Zoology
2007 - 2012 National Institute of Mental Health, Postdoctoral Fellow
2012 - 2016 National Institute of Mental Health, Research Fellow
2016.08 - Institute of Biophysics, Chinese Academy of Sciences, Principal Investigator
- Awards
- Membership in Academies & Societies
- Research Interests
Social cognition is essential for both individual and group survival, especially in socialanimals like humans and non-human primates. In a variety of psychiatric disorders, disruptedsocial cognition represents a common sensitive domain of their pathology. Although socialcognition has been studied for a long time, its brain underpinning remains elusive. Our long-termresearch goal is to understand the neural mechanisms underlying social cognitions, and develop new diagnostictools and treatment strategies for psychiatric diseases. Given the similarities in social cognition and its underlying neural circuitry between humans andnon-human primates, weuse non-human primates (e.g., rhesus macaque) as the model.Sophisticated non-invasive and invasive experimental approaches, including neuroimaging (e.g.,fMRI), interventional physiology (e.g., permanent/reversible lesion of brain circuits,microstimulation) and computational modeling, will be applied jointly toinvestigate these issues at various scales and levels.
- Grants
- Selected Publications
(* Corresponding Author, # First Author)
1. Zhang B, Chen Y, Zhang Y, Qiao Y, Wu Y, Zhang Y, Lu Y, You X, Li Y, Huang H, Wang Q, Li Y, Wang Y, Xiao W, Duan H, Qiu M, Chen N, Yu X, Yang M, Lv L, Cooper DN, Zheng P, Yao Y*, Liu N*, Wang J*, Wu D* (2025, Sep 30). Forward and reverse genomic screens enhance the understanding of phenotypic variation in a large Chinese rhesus macaque cohort. Nat Commun, 16(1), 8703. https://doi.org/10.1038/s41467-025-63747-x
2. Zhang Z, Dong X, Zou X, Liu N*. Hierarchical relationship between neural mechanisms of ensemble and individual perception revealed through perceptual learning. (2025, Oct) J Exp Psychol Gen. 154(10):2914-2925. https://doi.org/10.1037/xge0001832
3. Zhang Y, Qiao Y, Ji Y, Huang H, Zhang L, Ruan J, Li C, Xie H, Zhang B, Zhou Q, Yue S, Yu X, Qiu M, Yu C, Wu S, Zhou Y, Li Y, Zhu H, Dong S, Huang K, Wang Y, Wang Q, Li Y, Xie Y, Chen H, Lv L, Liu S, Yao Y, Wang C*, Liu N*, Wang J*. (2025, Jul 31). A Study of Spontaneous Self-Injurious Behavior and Neuroimaging in Rhesus Macaques. Research (Wash D C), 8, 0782. https://doi.org/10.34133/research.0782
4. Xin Y, Cui Y, Yu S, Liu N*. Genetic contributions to brain criticality and its relationship with human cognitive functions. (2025, Jun 23) Proc Natl Acad Sci U S A. 122 (26) e2417010122. https://doi.org/10.1073/pnas.2417010122
5. Lei J#, Xin Z#, Liu N#, Ning T#, Jing Y#, Qiao Y#, He Z, Jiang M, Yang Y, Zhang Z, Zhao L, Li J, Lv D, Yan Y, Zhang H, Xiao L, Zhang B, Huang H, Sun S, Zheng F, Jiang X, Lu H, Dong X, Yue S, Ma C, Shuai J, Ji Z, Liu F, Ye Y, Yan K, Hu Q, Xu G, Zhao Q, Wu R, Cai Y, Fan Y, Jing Y, Wang Q, Reddy P, Lu X, Zheng Z, Liu B, Haghani A, Ma S, Suzuki K, Esteban CR13,23, Yang J, Song M, Horvath S, Zhang W, Li W, Xiang AP, Zhu L, Fu X, Zhao G, Belmonte JCI, Qu J*, Wang S*, Liu G*. Senescence-resistant human mesenchymal progenitor cells counter aging in primates. (2025, Jun 13) Cell. S0092-8674(25)00571-9. https://doi.org/10.1016/j.cell.2025.05.021
6. Cheng Y#, Xin Y#, Lu X, Yang T, Ma X, Yuan X*, Liu N*, Jiang Y*. (2025, May) Shared and unique neural codes for biological motion perception in humans and macaque monkeys. Advanced Science, 12(18). https://doi.org/10.1002/advs.202411562
7. Ruan J, Yuan Y, Qiao Y, Qiu M, Dong X, Cui Y, Wang J, Liu N*. (2024, Dec 17) Connectional differences between humans and macaques in the MT+ complex. iScience, 28(1). https://doi.org/10.1016/j.isci.2024.111617
8. Lu X#, Hu Z#, Xin Y#, Yang T, Wang Y, Zhang P, Liu N*, Jiang Y*. (2024, Nov 7) Detecting Biological Motion Signals in Human and Monkey Superior Colliculus: A Subcortical-Cortical Pathway for Biological Motion Perception. Nat Commun, 15(1), 9606. https://doi.org/10.1038/s41467-024-53968-x
9. Zhao M, Xin Y, Deng H, Zuo Z, Wang X*, Bi Y*, & Liu N*. (2024, Oct 28). Object color knowledge representation occurs in the macaque brain despite the absence of a developed language system. PLoS Biol, 22(10), e3002863. https://doi.org/10.1371/journal.pbio.3002863
10. Zhao M, Li R, Xiang S, & Liu N*. (2024, Oct 3). Two different mirror neuron pathways for social and non-social actions? A meta-analysis of fMRI studies. Soc Cogn Affect Neurosci. https://doi.org/10.1093/scan/nsae068
11. Yang Y#, Lu X#, Liu N#, Ma S#, Zhang H#, Zhang Z#, Yang K, Jiang M, Zheng Z, Qiao Y, Hu Q, Huang Y, Zhang Y, Xiong M, Liu L, Jiang X, Reddy P, Dong X, Xu F, Wang Q, Zhao Q, Lei J, Sun S, Jing Y, Li J, Cai Y, Fan Y, Yan K, Jing Y, Haghani A, Xing M, Zhang X, Zhu G, Song W, Horvath S, Rodriguez Esteban C, Song M, Wang S, Zhao G, Li W, Izpisua Belmonte JC, Qu J, Zhang W, & Liu G. (2024, Sep 12). Metformin decelerates aging clock in male monkeys. Cell. https://doi.org/10.1016/j.cell.2024.08.021
12. Liu N*, Avidan G, Turchi JN, Hadj-Bouziane F, & Behrmann M. (2024, Jun 26). A Possible Neural Basis for Attentional Capture of Faces Revealed by Functional Magnetic Resonance Imaging and Causal Pharmacological Inactivation in Macaques. J Cogn Neurosci, 1-19. https://doi.org/10.1162/jocn_a_02211
13. Zhang Z, Dong X, Liu Z, & Liu N*. (2024, Jun 21). Social status predicts physiological and behavioral responses to chronic stress in rhesus monkeys. iScience, 27(6). https://doi.org/10.1016/j.isci.2024.110073
14. Zhang Q, Zhang Y, Liu N*, & Sun X*. (2024, Apr 9). Understanding of facial features in face perception: insights from deep convolutional neural networks. Front Comput Neurosci, 18. https://doi.org/10.3389/fncom.2024.1209082
15. Wu Y#, Zhao M#, Deng H, Wang T, Xin Y, Dai W, Huang J, Zhou T, Sun X, Liu N*, & Xing D*. (2024, Jan 15). The neural origin for asymmetric coding of surface color in the primate visual cortex. Nat Commun, 15(1), 516. https://doi.org/10.1038/s41467-024-44809-y
16. Sun F, Yang T, Liu N*, & Wan X*. (2023, Oct 13). The causal role of temporoparietal junction in mediating self-other mergence during mentalizing. J Neurosci. https://doi.org/10.1523/JNEUROSCI.1026-23.2023
17. Xiang S#, Zhao M#, Yu L, & Liu N*. (2023, Aug 11). A common self-advantage across the implicit and explicit levels for self-body recognition. Front Psychol, 14, 1099151. https://doi.org/10.3389/fpsyg.2023.1099151
18. Zhang H*, Ding X, Liu N, Nolan R, Ungerleider LG, & Japee S. (2023, Jun). Equivalent processing of facial expression and identity by macaque visual system and task-optimized neural network. Neuroimage, 273, 120067. https://doi.org/10.1016/j.neuroimage.2023.120067
19. Cui S, Yang T, & Liu N*. (2023, Jun 15). Generalization of the modulatory effect of social interaction on personal space. Front Psychol, 14, 1148395. https://doi.org/10.3389/fpsyg.2023.1148395
20. Shen B, Zhang Z, Wang Q, Tu Z*, Liu N*. (2023, May 25) A new approach to detecting and analyzing monkey activities using the improved YOLOv5. Third International Conference on Machine Learning and Computer Application (ICMLCA 2022).
21. Cheng Z, Liu N*, Fan Y*, Zuo P, Yuan H, Xu Z. (2022) Representations of object animacy and real-world size in the ventral visual pathway. Acta Physiologica Sinica, 74(2): 294-300. https://doi.org/10.13294/j.aps.2022.0028
22. Xin Y#, Bai T#, Zhang T, Chen Y, Wang K, Yu S*, Liu N*, & Tian Y*. (2022, Jan-Feb). Electroconvulsive therapy modulates critical brain dynamics in major depressive disorder patients. Brain Stimul, 15(1), 214-225. https://doi.org/10.1016/j.brs.2021.12.008
23. Liu N*, Behrmann M, Turchi JN, Avidan G, Hadj-Bouziane F, & Ungerleider LG. (2022, Nov 9). Bidirectional and parallel relationships in macaque face circuit revealed by fMRI and causal pharmacological inactivation. Nat Commun, 13(1), 6787. https://doi.org/10.1038/s41467-022-34451-x
24. Li N, & Liu N*. (2021, Jul 14). The Nonlinear and Gender-Related Relationships of Face Attractiveness and Typicality With Perceived Trustworthiness. Front Psychol, 12, 656084. https://doi.org/10.3389/fpsyg.2021.656084
25. Meng Q*, Wang B, Cui D, Liu N, Huang Y*, Chen L, & Ma Y. (2019, Jan 2). Age-related changes in local and global visual perception. J Vis, 19(1), 10. https://doi.org/10.1167/19.1.10
26. Taubert J*, Flessert M, Liu N, & Ungerleider LG. (2019, Oct 23). Intranasal oxytocin selectively modulates the behavior of rhesus monkeys in an expression matching task. Sci Rep, 9(1), 15187. https://doi.org/10.1038/s41598-019-51422-3
27. Tomeo OB, Ungerleider LG, & Liu N*. (2017, Jul 11). Preference for Averageness in Faces Does Not Generalize to Non-Human Primates. Front Behav Neurosci, 11, 129. https://doi.org/10.3389/fnbeh.2017.00129
加入生物物理所之前
28. Zhang H*, Japee S, Nolan R, Chu C, Liu N, & Ungerleider LG. (2016, Apr 15). Face-selective regions differ in their ability to classify facial expressions. Neuroimage, 130, 77-90. https://doi.org/10.1016/j.neuroimage.2016.01.045
29. Liu N, Hadj-Bouziane F, Moran, R, Ungerleider LG, & Ishai A*. (2016, Jan 11). Facial Expressions Evoke Differential Neural Coupling in Macaques. Cereb Cortex. https://doi.org/10.1093/cercor/bhv345
30. Liu N*, Hadj-Bouziane F, Jones, K. B, Turchi JN, Averbeck BB, & Ungerleider LG*. (2015, Jun 16). Oxytocin modulates fMRI responses to facial expression in macaques. Proc Natl Acad Sci U S A, 112(24), E3123-3130. https://doi.org/10.1073/pnas.1508097112
31. Avidan G*, Tanzer M, Hadj-Bouziane F, Liu N, Ungerleider LG, & Behrmann M. (2014, Jun). Selective dissociation between core and extended regions of the face processing network in congenital prosopagnosia. Cereb Cortex, 24(6), 1565-1578. https://doi.org/10.1093/cercor/bht007
32. Liu N*, Kriegeskorte N, Mur M, Hadj-Bouziane F, Luh WM, Tootell RB, & Ungerleider LG. (2013, Jul 10). Intrinsic structure of visual exemplar and category representations in macaque brain. J Neurosci, 33(28), 11346-11360. https://doi.org/10.1523/JNEUROSCI.4180-12.2013
33. Hadj-Bouziane F, Liu N, Bell, A. H, Gothard, K. M, Luh, W. M, Tootell RB, Murray EA, & Ungerleider LG. (2012, Dec 26). Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex. Proc Natl Acad Sci U S A, 109(52), E3640-3648. https://doi.org/10.1073/pnas.1218406109
34. Furl N#, Hadj-Bouziane F#, Liu N, Averbeck BB, & Ungerleider LG. (2012, Nov 7). Dynamic and static facial expressions decoded from motion-sensitive areas in the macaque monkey. J Neurosci, 32(45), 15952-15962. https://doi.org/10.1523/JNEUROSCI.1992-12.2012
35. Talbot T*, Ide D, Liu N, & Turchi J. (2011, Dec 4). A novel, variable angle guide grid for neuronal activity studies. Front Integr Neurosci, 6, 1. https://doi.org/10.3389/fnint.2012.00001
36. Nasr S, Liu N, Devaney KJ, Yue X, Rajimehr R, Ungerleider LG, & Tootell RB. (2011, Sep 28). Scene-selective cortical regions in human and nonhuman primates. J Neurosci, 31(39), 13771-13785. https://doi.org/10.1523/JNEUROSCI.2792-11.2011
37. Wu CW, Vasalatiy O, Liu N, Wu H, Cheal S, Chen DY, Koretsky AP, Griffiths GL, Tootell RB, & Ungerleider LG. (2011, Apr 28). Development of a MR-visible compound for tracing neuroanatomical connections in vivo. Neuron, 70(2), 229-243. https://doi.org/10.1016/j.neuron.2011.03.010
(From Ning Liu, October 11, 2025)