Mengdi Wang, Ph.D, Prof.
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Principal Investigator
State Key Laboratory of Cognitive Science and Mental Health, IBP
Research Interests: Artificial Intelligence and Computational Biology-Driven Intelligent Deciphering and Modeling of Nervous System
Email: mengdi_wang@ibp.ac.cn
Tel: 010-64888125
Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Chinese personal homepage
- Biography
2011 - 2015 B.Sc. in Bioengineering, Aachen University of Applied Sciences, Aachen, Germany
2015 - 2017 M.Sc. in Bioinformatics, University of Hamburg, Hamburg, Germany
2021 - 2025 Ph.D. in Cognitive Neurobiology, University of Chinese Academy of Sciences (UCAS), Beijing, China
- Awards
- Membership in Academies & Societies
- Research Interests
- Grants
- Selected Publications
(co-first author indicated by *)
1. Lu T*, Wang M*, Zhou W, Ni Q, et al. Decoding transcriptional identity in developing human sensory neurons and organoid modeling. Cell, 2024; 187(26): 7374-7393.e28. doi:10.1016/j.cell.2024.10.023
2. Shi Y*, Wang M*, Mi D*, Lu T, et al. Mouse and human share conserved transcriptional programs for interneuron development. Science, 2021; 374(6573): eabj6641. doi:10.1126/science.abj6641
3. Zhang J*, Li M*, Wang M*. et al. Single-cell spatiotemporal transcriptomic and chromatin accessibility profiling in developing postnatal human and macaque prefrontal cortex. Nat Neurosci (2025). doi:.10.1038/s41593-025-02150-7
4. Zhang L*, Yu M*, Chen G*, Ge S*, Wang M*, et al. Genetically encoded fluorescent reporters to visualize Lewy pathology in live brain. Cell (in press)
5. Wang M*, Zhuo L*, Ma W, Wu Q, et al. AllenDigger: a tool for spatial expression data visualization, spatial heterogeneity delineation, and single-cell registration based on the Allen Brain Atlas. J. Phys. Chem. A, 2023; 127(12): 2864-2872. doi:10.1021/acs.jpca.3c00145
6. Zhuo L*, Wang M*, Song T*, Zhong S, et al. MAPbrain: a multi-omics atlas of the primate brain. Nucleic Acids Res., 2025; 53(D1): D1055-D1065. doi:10.1093/nar/gkae911
7. Zhong S*, Wang M*, Huang L*, Chen Y*, et al. Single-cell epigenomics and spatiotemporal transcriptomics reveal human cerebellar development. Nat. Commun., 2023; 14(1): 7613. doi:10.1038/s41467-023-43568-68.
8. Wang W*, Wang M*, Yang M*, Zeng B*, et al. Transcriptome dynamics of hippocampal neurogenesis in macaques across the lifespan and aged humans. Cell Res., 2022; 32(8): 729-743. doi:10.1038/s41422-022-00678-y
9. Zhang Q*, Cheng S*, Wang Y*, Wang M*, et al. Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages. Nat. Commun., 2021; 12(1): 6867. doi:10.1038/s41467-021-27018-9
10. Xie Z*, Wang M*, Liu Z*, Shang C*, et al. Transcriptomic encoding of sensorimotor transformation in the midbrain. Elife, 2021; 10: e69825. doi:10.7554/eLife.69825
11. Liu J*, Wang M*, Sun L*, Pan NC, et al. Integrative analysis of in vivo recording with single-cell RNA-seq data reveals molecular properties of light-sensitive neurons in mouse V1. Protein Cell, 2020; 11(6): 417-432. doi:10.1007/s13238-020-00720-y
12. Shi Y*, Sun L*, Wang M*, Liu J*, et al. Vascularized human cortical organoids (vOrganoids) model cortical development in vivo. PLoS Biol., 2020; 18(5): e3000705. doi:10.1371/journal.pbio.3000705
(From Mengdi Wang, July 15, 2026)