Kelong Fan, Ph.D, Prof.
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Principal Investigator (IBP-Fellow)
Key Laboratory of Protein and Peptide Drugs，IBP
Young Elite Scientist Sponsorship Program by CAST
Research Interests: Nanobiology
Email: fankelong@ibp.ac.cn
Tel: 010-64888280
Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Chinese personal homepage
- Biography
2005.09 - 2009.07 B.Sc. in Bioengineering, China University of Mining and Technology (Beijing), Beijing
2009.09 - 2014.07 Ph.D. in Cell Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing
2014.08 - 2017.12 ‘Morningside-IBP’ Postdoctoral Program, Institute of Biophysics, Chinese Academy of Sciences, Beijing
2018.01 - 2019.07 Associate Professor, Institute of Biophysics, Chinese Academy of Sciences, Beijing
2019.07 - Professor, Institute of Biophysics, Chinese Academy of Sciences, Beijing
- Awards
- Membership in Academies & Societies
1. Invited Reviewer for Materials Today, Advanced Materials, Angew. Chem. Int. Ed., J. Am. Chem. Soc., Nano Today, ACS Nano, Nano Letters, Biomaterials, Small, Biosensor Bioelectronics, Analytical Chemistry, Bioconjugate Chemistry and Materials Science & Engineering C.
Excellent Reviewer for Materials Science & Engineering C in 2018.
2. Invited Guest Editor for Frontiers in Chemistry, Journal of Oncology.
3. Member and deputy secretary general of Nanozyme Branch of Chinese Biophysical Society.
4. Member of Material Biology and Intelligent Diagnosis and Treatment Sub-committee of Chinese Biophysical Society.
5. Member of Angiography Sub-committee of China Medical biotechnology Association.
6. Member of the Youth Committee of Nano-Tumor Professional Committee, Chinese Anti-Cancer Association.
7. Member of the Youth Committee of Nano-Biology branch of Chinese Society of Biophysics.
- Research Interests
- Grants
- Selected Publications
1. Long Ma, Jia-Jia Zheng, Ning Zhou, Ruofei Zhang, Long Fang, Yili Yang, Xingfa Gao, Chunying Chen, Xiyun Yan*, Kelong Fan*. A natural biogenic nanozyme for scavenging superoxide radicals. Nature Communications. 2024,15, 233.
2. Xiangqin Meng, Huizhen Fan, Lei Chen, Jiuyang He, Chaoyi Hong, Jiaying Xie, Yinyin Hou, Kaidi Wang, Xingfa Gao, Lizeng Gao, Xiyun Yan*, Kelong Fan*. Ultrasmall metal alloy nanozymes mimicking neutrophil enzymatic cascades for tumor catalytic therapy. Nature Communications. 2024, 15, 1626.
3. Wei Jiang, Qing Li*, Ruofei Zhang, Jianru Li, Qianyu Lin, Jingyun Li, Xinyao Zhou, Xiyun Yan*, Kelong Fan*. Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson's disease. Nature Communications, 2023, 14, 8137.
4. Wenhui Gao, Jiuyang He, Lei Chen, Xiangqin Meng, Yana Ma, Liangliang Cheng, Kangsheng Tu, Xingfa Gao, Cui Liu*, Mingzhen Zhang*, Kelong Fan*, Dai-Wen Pang*, Xiyun Yan*. Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme. Nature Communications. 2023, 14, 160.（ESI高被引论文）
5. Ruofei Zhang, Bing Jiang, Kelong Fan*, Lizeng Gao*, Xiyun Yan*. Designing nanozymes for in vivo applications. Nature Reviews Bioengineering. 2024, 2(10): 849-868.
6. Shuyu Wang, Miaomiao Cheng, Shenghui Wang, Wei Jiang, Feifei Yang, Xiaomei Shen, Lirong Zhang, Xiyun Yan*, Bing Jiang*, Kelong Fan*, A Self-Catalytic NO/O2 Gas-Releasing Nanozyme for Radiotherapy Sensitization through Vascular Normalization and Hypoxia Relief. Advanced Materials. 2024, 36(39): 2403921.
7. Zhuoran Wang, Yue Zhao, Yaxin Hou, Guoheng Tang, Ruofei Zhang, Yili Yang, Xiyun Yan*, Kelong Fan*. A Thrombin-Activated Peptide-Templated Nanozyme for Remedying Ischemic Stroke via Thrombolytic and Neuroprotective Actions. Advanced Materials. 2024, 36 (10): 202210144.（ESI高被引论文）
8. Daji Wang*, Jie Wang*, Xuejiao J. Gao, Hui Ding, Ming Yang, Zhiheng He, Jiaying Xie, Zixia Zhang, Haibing Huang, Guohui Nie*, Xiyun Yan*, Kelong Fan*. Employing Noble Metal-Porphyrins to Engineer Robust and Highly Active Single-Atom Nanozymes for Targeted Catalytic Therapy in Nasopharyngeal Carcinoma. Advanced Materials. 2024, 36(7), 2310033.
9. Jingqi Li, Xinda Cai, Peng Jiang, Huayuan Wang, Shiwei Zhang, Tiedong Sun*, Chunxia Chen*, Kelong Fan*. Co-based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences. Advanced Materials, 2024, 36(8), 2307337.
10. Yongjuan Li, Yu Zhang, Ya Dong, Ozioma Udochukwu Akakuru, Xiaohan Yao, Jinmeng Yi, Xinyan Li, Linlin Wang, Xiaohan Lou, Baoyu Zhu, Kelong Fan*, Zhihai Qin*. Ablation of Gap Junction Protein Improves the Efficiency of Nanozyme-Mediated Catalytic/Starvation/Mild-Temperature Photothermal Therapy. Advanced Materials, 2023, 22, 2210464.
11. Ruofei Zhang#, Bai Xue#, Yanhong Tao#, Hanqing Zhao, Zixia Zhang, Xiaonan Wang, Xinyao Zhou, Bing Jiang, Zhenglin Yang*, Xiyun Yan*, and Kelong Fan*. Edge-site Engineering of Defective Fe-N4 nanozymes with Boosted Catalase-like Performance for Retinal Vasculopathies. Advanced Materials. 2022, 34(39): 2205324.（ESI高被引论文）
(From Kelong Fan, November 21, 2024)