Nature Chemical Biology, 17 November, 2022, DOI：https://doi.org/10.1038/s41589-022-01195-0

Gathering on the cell surface

Zheng Wang & Hong Zhang

Abstract

Clustering and multimerization of cell surface proteins (CSPs) are essential for triggering downstream intracellular signaling events. Membrane-anchored liquid–liquid phase-separation systems have now been developed to manipulate the spatiotemporal distribution and activation of CSPs.

Article link：https://www.nature.com/articles/s41589-022-01195-0