1988 - 1992  B.S. in Engineering, Huazhong University of Science and Technology

1992 - 1996  Ph.D. in Physics, Huazhong University of Science and Technology

1996 - 1999  Postdoctoral Fellow, Max-Planck-Institute for Biophysical Chemistry, Germany

1999 - 2000  Senior Fellow, Department of Physiology and Biophysics, University of Washington, USA

2000 - 2003  Professor, Institute of Biophysics and Biochemistry, Huazhong University of Science and Technology, China

2003 -           Professor, Institute of Biophysics, Chinese Academy of Sciences, China

1997-1999  Max-Planck-Institute Fellowship

2000           Cheung Kong Scholars, China

2001/2002  Li Foundation Heritage Prize, USA

2004           Expert entitled to Government Special Allowance

2004           Young expert with outstanding contributions

2006           The 10th May 4th Youth Medal, China

2007           Young Affiliate, TWAS

2008           National Natural Science Award (the Second Class), China

1. Focus on the development of cutting-edge new technologies in cryo-superresolution light and electron microscopy to study the structure in situ and function of organelles and related proteins in cells at nanoscale;

2. With multi omics technology, integrating multi-dimensional omics data such as clinical phenotype, genotype and expression profile, analyzing disease related factors from the health and disease population, tissue, cell and molecular levels, to deeply explore the etiology and precise diagnosis and treatment of diseases such as diabetes and respiratory system related diseases;

3. Developing ultrasensitive next generation detection technologies based on small extracellular vesicles-exosomes, to carry out convenient and non-invasive early diagnosis and dynamic monitoring of diseases.

1. Zhuo Ma, Xiaofei Zhang, Wen Zhong, Hongyan Yi, Xiaowei Chen, Yinsuo Zhao, Yanlin Ma*, Eli Song*, Tao Xu*. Deciphering early human pancreas development at the single-cell level. Nature Communications, 2023, 14(1): 5354.

2. Weixing Li, Jing Lu, Ke Xiao, Maoge Zhou, Yuanyuan Li, Xiang Zhang, Zhixun Li, Lusheng Gu, Xiaojun Xu, Qiang Guo*, Tao Xu*, Wei Ji*.Integrated multimodality microscope for accurate and efficient target-guided cryo-lamellae preparation. Nature Methods 2023 Feb;20(2):268-275.

3. Wanyan Wu, Shihang Luo, Chunyan Fan, Tianjie Yang, Shuwen Zhang, Wenxiang Meng, Tao Xu*, Wei Ji*, Lusheng*. Tetra-color superresolution microscopy based on excitation spectral demixing. Light: Science & Applications 2023, 12(1):9

4. Huaxia Luo, Peng Zhang, Wanyu Zhang, Yu Zheng, Di Hao, Yirong Shi, Yiwei Niu, Tingrui Song, Yanyan Li, Shilei Zhao, Hua Chen*, Tao Xu*, Shunmin He*. Recent positive selection signatures reveal phenotypic evolution in the Han Chinese population. Science Bulletin 2023, 68(20), 2391-2404.

5. Yirong Shi, Yiwei Niu, Peng Zhang, Huaxia Luo, Shuai Liu, Sijia Zhang, Jiajia Wang, Yanyan Li, Xinyue Liu, Tingrui Song, Tao Xu*, Shunmin He*. Characterization of genome-wide STR variation in 6487 human genomes. Nature Communications 2023, 14(1): 2092.

6. Liqing Liu, Shuxin Yang, Yang Liu, Xixia Li, Junjie Hu*, Li Xiao* and Tao Xu*, DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging. Journal of Cell Biology 2022, 221(9): e2021061900.

7. Min Li, Fengping Feng, Han Feng, Pengkai Hu, Yanhong Xue, Tao Xu*, Eli Song*, VAMP4 regulates insulin levels by targeting secretory granules to lysosomes. Journal of Cell Biology 2022, 221(10):e202110164.

8. Wang, L.; Liu, H.; Zhang, X.; Song, E.; Wang, Y.; Xu, T.*; Li, Z.*, WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells. Nature communications 2021, 12 (1), 6996.

9. Lusheng Gu, Yuanyuan Li, Shuwen Zhang, Maoge Zhou, Yanhong Xue, Weixing Li, Tao Xu* and Wei Ji*, Molecular-scale axial localization by repetitive optical selective exposure, Nature Methods 2021, 18: 369-373.

10. Zhifei Fu, Dingming Peng, Mingshu Zhang*, Fudong Xue, Rui Zhang, Wenting He, Tao Xu* and Pingyong Xu*, mEosEM withstands osmium staining and Epon embedding for super-resolution CLEM, Nature Methods 2020,17:(55-58).

11. Mingshu Zhang, Zhifei Fu, Changqing Li, Anyuan Liu, Dingming Peng, Fudong Xue, Wenting He, Shan Gao, Fan Xu, Dan Xu, Ling Yuan, Fa Zhang, Zhiheng Xu, Tao Xu*, Pingyong Xu*, Fast super-resolution imaging technique and immediate early nanostructure capturing by a photo-convertible fluorescent protein, Nano Letters 2020, 20(4): 2197-2208.

12. Lusheng Gu, Yuanyuan Li, Shuwen Zhang, Yanhong Xue, Weixing Li, Dong Li, Tao Xu*, Wei Ji*, Molecular resolution imaging by repetitive optical selective exposure (ROSE), Nature Methods 2019，16(11):1114-1118

13. Wenjuan Zou, Jiajun Fu, Haining Zhang, Kang Du, Wenming Huang, Junwei Yu, Shitian Li, Yuedan Fan, Howard A. Baylis, Shangbang Gao, Rui Xiao, Wei Ji*, Lijun Kang* and Tao Xu*. Decoding the intensity of sensory input by two glutamate receptors in one C. elegans interneuron. Nature Communications 2018, 9:4311.

14. Zonghong Li, Maoge Zhou, Zhaokui Cai, Wen Zhong, Qiang Hao, Dongwan Chen, Xihao Hu, Junjie Hou, Pingyong Xu, Yuanchao Xue, Yifa Zhou, Tao Xu*. RNA binding protein DDX1 is responsible for fatty acid mediated repression of insulin translation. Nucleic Acids Research 2018. 1-16. 　

(From Tao Xu, June 13, 2024)