2006.09 - 2010.06  Huazhong University of Science and Technology, Biomedical Engineering, B.S.

2010.09 - 2015.06  Huazhong University of Science and Technology, Biophysics, Ph.D.

2015.07 - 2016.07  Institute of Biophysics, CAS, Research Associate

2016.07 - 2017.12  Institute of Biophysics, CAS, Engineer

2018.01 -                Institute of Biophysics, CAS, Senior Engineer

Mainly focused on light super-resolution imaging technology, development of light microscopy instruments and correlated light and electron microscopy (CLEM). Utilize the state of the art imaging technology to solve frontier biological problems and to create new discoveries. We developed several imaging systems such as interference photon-activation localization microscopy (iPALM), and correlated light and electron microscopy (CLEM).

1. Wang L*, Lu J*, Ji W^#, Wan L^#, Gu L^#. Interferometrical single-molecule localization based on dynamic PSF engineering. Optics Letters. 47, 1770-1773 (2022)

2. Gu L*, Li Y*, Zhang S*, Zhou M, Xue Y, Li W, Xu T^#, Ji W^#. Molecular-scale axial localization by repetitive optical selective exposure. Nature Methods. 18, 369-373(2021)

3. Gu L*, Li Y*, Zhang S*, Xue Y, Li W, Li D, Xu T^#, Ji W^#. Molecular resolution imaging by repetitive optical selective exposure. Nature Methods. 16, 1114-1118(2019)

4. Lusheng Gu*, Yi Sheng*, Yan Chen*, Hao Chang, Yongdeng Zhang, PingPing Lv, Wei ji^# and Tao Xu^#. High-density 3D single molecular analysis based on compressed sensing. Biophysical Journal. 106(11), 2443-2449

5. Yongdeng Zhang*, Lusheng Gu*, Hao Chang*, Wei Ji*, Yan Chen, Mingshu Zhang, Lu Yang, Bei Liu, Liangyi Chen^#, and Tao Xu^#. (2013). Ultrafast, accurate, and robust localization of anisotropic dipoles. Protein Cell. 4(8), 598-606

6. Yondeng Zhang*, Hao Chang*, Lusheng Gu, Yanhua Zhao, Tao Xu^# & Wei Ji^#. Super-resolution microscopy of live cells using single molecule localization. Chinese Sci Bull. 58 (36), 4519-4527

(From Lusheng Gu, October 24, 2022)