Home > Faculty

Fahui Li, Ph.D, Associate Professor

Member of the Youth Innovation Promotion Association of CAS


Research Interests: Chemical biology and cell biology


Email: lifahui@ibp.ac.cn


Tel: 010-64852570


Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China


Chinese personal homepage


 

Biography

1998.09 - 2002.07  Bachelor, Northwest A&F University

2002.09 - 2005.07  Master, Northwest A&F University, Beijing Institute of Radiation Medicine

2005.09 - 2009.07  Ph.D, Institute of Microbiology, Chinese Academy of Sciences

2009.07 -                Institute of Biophysics, Chinese Academy of Sciences

Awards
 
Membership in Academies & Societies
 
Research Interests

My research focuses on developing new methods for RNA labelling, which can be used to studying RNA location, RNA structure, RNA folding and RNA-RNA/protein interaction.

Grants
 
Selected Publications

1. Min Deng#, Fahui Li#, Bryan A. Ballif, Shan Li, Xi Chen, Lin Guo and Xin Ye*,Identification and Functional Analysis of a Novel Cyclin E/Cdk2 Substrate Ankrd17. Journal of Biological Chemistry, 2009, 284(12): 7875~7888

2. Fahui Li#, Pan Shi#, Jiasong Li#, Fan Yang, Tianyuan Wang, Wei Zhang, Feng Gao, Wei Ding, Dong Li, Juan Li, Ying Xiong, Jinpeng Sun, Weimin Gong*, Changlin Tian*, and Jiangyun Wang*, A genetically encoded 19F NMR probe for tyrosine phosphorylation. Angew Chem Int Ed Engl, 2013, 52(14): 3958~3962

3. Fahui Li#, Hua Zhang#, Yun Sun#, Yanchao Pan#, Juanzuo Zhou, and Jiangyun Wang*, Expanding the genetic code for photoclick chemistry in E.coli, mammalian cells, and A. thaliana. Angew Chem Int Ed Engl, 2013, 52 (37): 9700~9704

4. Fahui Li#, Jianshu Dong#, Xiaosong Hu#, Weimin Gong, Jiasong Li, Jing Shen, Huifang Tian, and Jiangyun Wang*, A covalent approach for site-specific RNA labeling in Mammalian cells. Angew Chem Int Ed Engl, 2015, 54(15): 4597~4602

5. Feng Zhang#, Qing Zhou#, Guiwen Yang, Liguo An*, Fahui Li* and Jiangyun Wang*, A genetically encoded (19)F NMR probe for lysine acetylation. Chem Commun (Camb), 2018, 54(31): 3879~3882

6. Zhaopeng Zheng#, Xuzhen Guo#, Minling Yu#, Xiaoyan Wang, Hongguang Lu*, Fahui Li*, and Jiangyun Wang, Identification of human IDO1 Enzyme Activity by Using Genetically Encoded Nitrotyrosine. Chembiochem, 2020, 21(11):1593-1596.

7. Fan Yang, Xiao Yu, Chuan Liu, Chang-Xiu Qu, Zheng Gong, Hong-Da Liu, Fa-Hui Li, Hong-Mei Wang, Dong-Fang He, Fan Yi, Chen Song, Chang-Lin Tian, Kun-Hong Xiao, Jiang-Yun Wang* and Jin-Peng Sun*, Phospho-selective mechanisms of arrestin conformations and functions revealed by unnaturalamino acid incorporation and (19)F-NMR. Nature Communications, 2015, 6:8202~8202

8. Tianyuan Wang#, Qing Zhou#*, Fahui Li, Yang Yu, Xuebin Yin*,and Jiangyun Wang*, Genetic Incorporation of N(epsilon)-Formyllysine, a NewHistone  Post-translational Modification. ChemBioChem, 2015, 16(10):1440~1442

9. Jiasong Li, Wendell P. Griffith, Ian Davis, Inchul Shin, Jiangyun Wang, Fahui Li, Yifan Wang, Daniel J. Wherritt,and Aimin Liu*, Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat Chem Biol, 2018, 14(9):853-860

10. Jianshu Dong, Fahui Li, Feng Gao, Jia Wei, Yajing Lin, Yong Zhang, Jizhong Lou, Guangfeng Liu, Yuhui Dong, Lin Liu, Jiangyun Wang and Weimin Gong*, Structure of tRNA Modifying Enzyme TiaS and Motions of its Substrate Binding Zinc Ribbon. J Mol Biol, 2018, 430(21):4183-4194

11. Lin Xia, Ming-Jie Han, Lu Zhou, Aiping Huang, Zhaoya Yang, Tianyuan Wang, Fahui Li, Lu Yu, Changlin Tian, Zhongsheng Zang, Qing-Zheng Yang, Chenli Liu, Wenxu Hong, Yi Lu, Lital Alfonta, and Jiangyun Wang*, S-Click Reaction for Isotropic Orientation of Oxidases on Electrodes to Promote Electron Transfer at Low Potentials. Angew Chem Int Ed Engl, 2019, 58: 1-6

12. Shen-Ming Huang, Fan yang, Bai-Yang Cai, Qing-Tao He, Qi Liu, Chang-Xiu Qu, Ming-Jie Han, Wei Kong, Ying-Li Jia, Fahui Li, Xiao Yu, Jin-Peng Sun, and Jiangyun Wang, A Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET. Anal Chem. 2019, 91(23): 14936- 1494210.

13. Qi Liu#, Qing-tao He#, Xiaoxuan Lyu#, Fan Yang#, Zhong-liang Zhu#, Peng Xiao, Zhao Yang, Feng Zhang, Zhao-ya Yang, Xiao-yan Wang, Peng Sun, Qian-wen Wang, Chang-xiu Qu, Zheng Gong, Jing-yu Lin, Zhen Xu, Shao-le Song, Shen-ming Huang, Sheng-chao Guo, Ming-jie Han, Kong-kai Zhu, Xin Chen, Alem W. Kahsai, Kun-Hong Xiao, Wei Kong, Fa-hui Li, Ke Ruan, Zi-jian Li, Xiao Yu, Xiao-gang Niu, Chang-wen Jin, Jiangyun Wang* and Jin-peng Sun*. DeSiphering receptor core-induced and liganddependent conformational changes in arrestin via genetic encoded trimethylsilyl 1H-NMR probe. Nat Commun, 2020, 11(1):4857

 

(From Fahui Li, April 1, 2021)

 

Contact Us

Tel: 010-64889872

E-Mail: webadmin@ibp.ac.cn

Address: No 15 Datun Road, Chaoyang District, Beijing

Postcode: 100101