On Aug 22, Professor Arkady A. Karyakin from Lomonosov Moscow State University visited the Institute of Biophysics (IBP) of the Chinese Academy of Sciences, at the invitation of Professor Yan Xiyun of the Nano-Enzyme Engineering Laboratory. Karyakin gave a lecture entitled "Prussian Blue: from the advanced transducer to nanozymes defeating natural peroxidase".

Karyakin is chairman of analytical chemistry at the Department of Chemistry and director of Electrochemical Methods Laboratory at Lomonosov Moscow State University.

Karyakin has found that Prussian blue has special electrochemical properties. From Prussian blue modified electrodes to nanoelectrodes, then to ultra-micro electrodes, the sensitivity to H2O2 detection can be significantly improved.

He has also combined biosensing and enzyme immobilization technologies to develop an advanced transducer that can detect glucose, glutamate and lactate, as well as non-invasive technologies that can detect diabetic patients' blood glucose status by detecting glucose concentrations in sweat and exhaled gases.

Different from conventional nanozymes, Prussian blue nanoparticles produced by catalytic synthesis have peroxidase activity but no oxidase activity, and the larger the size, the higher the enzymatic activity. Compared with natural peroxidase, synthesized Prussian blue has higher enzymatic activity and stability, and is expected to be used as a substitute for natural enzymes in biotechnology and analytical chemistry.

From 2010 to 2014, Karyakin worked as associate editor for Electroanalysis Journal, and has been the associate editor of Electrochemistry Communications since 2015. He was awarded the Bioelectrochemistry Award of the International Society of Electrochemistry (ISE) in 2012 and became a member of ISE in 2014. In 2015, he was awarded the M.V. Lomonosov Scientific Prize, the highest honor at Lomonosov Moscow State University.

Karyakin has published 145 papers in renowned academic journals such as J.Am.Chem.Soc, Anal.Chem, Electrochem.Commun, and Acs Catalysis.